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</script> </div> </div> <section class="news"> <div class="news_view"> <ul> <li> <h1>HK이노엔, ‘주 1회 주사’ GLP-1 계열 비만약 임상 3상 승인받아</h1> <div class="view_img"> <p>최초입력 2025.05.08 10:29:29</p> <button type="button" class="btn_view btn_plus2" onclick='controlContentFontSize(0)'><span class="ico_comm ico_plus">크게</span></button> <button type="button" class="btn_view btn_min2" onclick='controlContentFontSize(1)'><span class="ico_comm ico_min">작게</span></button> </div> <div class="share_box"> <img src="//bimg.mk.co.kr/mkbn/mob/ic_sc2.png" width="29" alt="페이스북" onclick="sendThis('facebook');" data-label="facebook" data-category="share" class="sns_section_li" sns_name="facebook"> <img src="//bimg.mk.co.kr/mkbn/mob/ic_sc3.png" width="29" alt="트위터" onclick="sendThis('twitter');" data-label="twitter" data-category="share" class="sns_section_li" sns_name="twitter"> <a href="javascript:void(0);" data-label="kakaotalk" data-category="share"><img class="sns_section_li" sns_name="kakaotalk" src="//bimg.mk.co.kr/mkbn/mob/ic_sc4.png" width="29" alt="카카오톡"></a> <span class='bandSpabStyle2'> <script type="text/javascript"> new ShareBand.makeButton({"lang": "ko", "type": "c", "text": "", "withUrl": true}); </script> </span> <a onclick="sendMail();" href="javascript:void(0);" data-label="email" data-category="share"><img src="//bimg.mk.co.kr/mkbn/mob/ic_sc1.png" width="29" alt="메일보내기"></a> </div> </li> <li> <p class="sub_tit">주 1회 피하주사 투여 방식 28년 5월 임상 완료 목표</p><!-- View Type : 9--> </li> <style> #artText .mid_title { display: none; } </style> <li> <div id="artText" class="view_txt" style="font-size: 16px;"><div class="mid_title"> <div class="midtitle_text">주 1회 피하주사 투여 방식<br/>28년 5월 임상 완료 목표 </div></div><div refId="1" class="thumb_area img"> <figure> <div class="thumb"> <img loading="lazy" src="https://wimg.mk.co.kr/news/cms/202505/08/news-p.v1.20250508.bcba3661c68244cd9a2dae6957b5068f_P1.jpg" orgWidth="700" orgHeight="572" alt="HK이노엔 스퀘어. 사진=HK이노엔" > <button class="btn btn_ic btn_zoom"> <i class="ic ic_zoom" data-url="https://wimg.mk.co.kr/news/cms/202505/08/news-p.v1.20250508.bcba3661c68244cd9a2dae6957b5068f_R.jpg" data-width="1000" data-height="817"></i> <span class="is_blind">사진 확대</span> </button> </div> <figcaption> <span class="thum_figure_txt">HK이노엔 스퀘어. 사진=HK이노엔</span> </figcaption> </figure></div><p refId="2">HK이노엔은 식품의약품안전처로부터 GLP-1(글루카곤 유사 펩타이드-1) 수용체 작용제 계열 비만 치료제로 개발 중인 ‘IN-B00009(성분명 에크노글루타이드)’의 국내 임상 3상 시험계획(IND) 승인을 받았다고 8일 밝혔다.</p><p refId="3">이번 3상 임상시험은 당뇨병을 동반하지 않은 성인 비만 또는 과체중 환자를 대상으로 진행된다. IN-B00009 또는 위약을 주 1회 피하주사로 투여해 유효성과 안전성을 평가한다. 시험은 다기관, 무작위배정, 이중 눈가림, 위약 대조, 평행군 방식으로 설계됐다. 2028년 5월 임상시험 완료가 목표다.</p><p refId="4">HK이노엔은 이번 시험에서 기저치 대비 40주 시점의 체중 변화율과 체중 감소율 5% 이상인 시험대상자 비율을 1차 평가지표로 설정했다.</p><p refId="5">IN-B00009는 앞서 호주와 뉴질랜드에서 비만 환자 대상으로 진행된 임상 2상에서 26주 투여 시 안전성 및 리라글루티드 대비 통계적으로 유의한 체중 감소 효과를 입증한 바 있다. 또한 중국에서 진행된 현지 비만 환자 대상 임상 3상에서도 위약 대비 우수한 체중 감소 효과를 확인했다.</p><p refId="6">전세계적으로 비만 인구가 증가하면서 비만 치료제 개발이 활발해지고 있다. 글로벌 비만치료제 시장 규모는 2023년 190억3700만달러(약 26조5813억원)에서 연평균 14.4% 성장해 2028년에는 373억 6710만달러(약 52조1457억원) 규모에 이를 것으로 전망된다.</p><p refId="7">IN-B00009는 HK이노엔이 지난해 중국 바이오기업 사이윈드 바이오사이언스에서 도입한 물질이다. HK이노엔은 해당 물질의 국내 개발 및 상업화 권리를 확보해 비만 치료제와 당뇨병 치료제로 개발 중이다. HK이노엔 관계자는 “IN-B00009가 전세계적 질병인 비만 치료에 기여할 수 있도록 모든 역량을 집중할 것”이라고 말했다.</p><div id="refTotal" value="7"></div> [ⓒ 매일경제 & mk.co.kr, 무단 전재, 재배포 및 AI학습 이용 금지]</div> </li> </ul> <div id="reple"> <script type='text/javascript'> window.livereOptions = { refer : 'mkbn.mk.co.kr/news/it/11311181', site : 'https://mkbn.mk.co.kr/news/it/11311181' }; </script> <div id='lv-container' data-id='mk' data-uid='MjQvMzYvMjc='> <script type='text/javascript'> (function(d, s) { var j, e = d.getElementsByTagName(s)[0]; if (typeof LivereTower === 'function') { return; } j = d.createElement(s); j.src = '//cdn-city.livere.com/js/embed.dist.js'; j.async = true; e.parentNode.insertBefore(j, e); })(document, 'script'); </script> <noscript></noscript> </div> </div> <script type="text/javascript"> $(".news_view").find(".center_image").each(function (idx) { var imgSrc = ''; var imgEl = ''; var that = ''; imgSrc = $(this).find("img").attr("src"); imgEl = $("<img/>"); that = $(this); imgEl.prop("src", imgSrc).on("load", function () { var w = this.width; 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